New Medical Hair Loss Treatments
For many patients hair transplant surgery is not the correct option. Either the patient has minimal hair loss so surgery is too extreme a solution or the patients lacks enough hair in a donor site to make a transplant a viable solution. For these patients a non-surgical medical treatment for hair restoration is ideal.
Medical hair restoration for hair loss offers a plethora of benefits. It has no downtime, few or negligible side effects, and a potential for significant results.
Currently, there are only two medical treatments available to the general public:
- Minoxidil topically
- Finasteride Orally
Recently, there's been a revolution in hair loss technologies. Armed with powerful new tools, scientists have learned how to read the complex chemical languages of hair loss and now researchers are rushing into studies with several new potential therapies. "In the last 5 to 7 years there has been a boom in the understanding of hair loss," George Cotsarelis, MD, director of the Hair and Scalp Clinic at the University of Pennsylvania, Philadelphia, told WebMD. "We've made great strides at the level of basic research. Now the question is how we can convert these findings into clinical benefits. Those kinds of leaps really take decades."
In 1993 when Dr. Robert Hashemiyoon was the first physician to use oral finasteride for hair loss there was no powerful internet to allow rapid and widespread dissemination of information as we have today. The only patients that benefited form the use of Dr. Robert's treatments were his local community patients. Nearly half a decade later oral Propecia became available to everyone.
Today we are happy that we can provide innovative, up to date information to everyone. And we can now provide new cutting edge medical treatments to a larger portion of the hair loss community that desperately needs these treatments. Our patients have the benefit of using these new treatments decades before they are FDA approved specifically for hair loss and available to the general public since we can provide them off-label legally to our patients.
To understand these new treatments better we have provided the research below:
BioHair X - Patent Application Number 62/627,333
BioHair X is unique in the world in that it contains 3 active ingredients (FDA approved) in a single bottle for ease and convenience of use. It also provides the patient with every possible beneficial ingredient that could help with the prevention of hair loss and the stimulation of hair regrowth. We have had tremendous success with Alopecia Areata and Alopecia Androgenetica (pattern) hair loss with both men and women.
We have had four patients in their 70s grow back significant hair. Some have even reported their hair darkening again (probably a result of the Bimatoprost pigment effects). Below are two examples of the results that can be achieved with BioHair X (results may vary):
40 year old male after 10 months of use
57 year old male after 30 days of use
How does BioHair X work? It combines 3 cutting edge technologies into one single bottle for a simple convenient once a day topical application. The combined mixture is patent pending. Each ingredient has been proven in several animal studies and in several human studies to grow hair back.
Hair Loss and ReGrowth
This FDA approved medication belongs to a group of medications classified as Janus kinase inhibitors (JAK inhibitors), small molecules that interrupt cytokine signaling. Two JAK inhibitors were approved around 2012 by the US Food and Drug Administration for the treatment of rheumatoid arthritis and bone marrow disorders.
In 2015 a series of ground-breaking experiments involving mice and human tissue was conducted by scientists and showed that enzyme-blocking drugs known as JAK inhibitors can cause significant regrowth of hair when applied to the skin.
The unexpected finding raises the possibility that these medications might be used to restore hair growth in men and women experiencing Alopecia Areata, Alopecia Androgenetica (pattern baldness), as well as in cancer patients who have lost hair as a result of chemotherapy treatments. Currently, ths FDA approved medication is being fast tracked by the FDA for hair loss. Here is an example of the results seen with this medication.
Originally developed as a treatment for glaucoma under the brand name Lumigan, this medication has been recently linked to use as a hair loss treatment. As a prostaglandin F2 alpha analogue that stimulates hair growth it has hormone-like effects on humans and animals.
This ingredient at 0.03 % is a well known eyelash growth stimulatory compound and marketed under the name Latisse (FDA approved 2008).
A 2013 study, performed at the University of Bradford in the UK, studied the effect of this medication on hair from several different angles. They concluded that it "stimulates the growth of mouse pelage hair. [it] was found as the intact molecule in mouse skin and blood, indicating that it stimulates hair growth by interacting with prostamide-sensitive receptors. These studies indicate that the ability of this ingredient to stimulate hair growth may extend beyond eyelashes,
From Allergan's own files we have examples of the results of this medication on hair regrowth:
To read the results from a recent study from the FASEB Journal click here.
Melatonin is primarily known as a neurohormone that is produced in the brain's pineal gland and is involved in regulating the body's physiological response to natural cycles of light and darkness, called circadian rhythms. More recent research showed that not only is melatonin produced by other organs, including the skin, but melatonin is produced by, and melatonin receptors are found in, hair follicles.
Research published in the International Journal of Trichology in 2012 found that the anti androgen and antioxidant properties of the hormone melatonin could be made into a topical solution for the treatment of early stage androgenetic alopecia, or common male and female pattern baldness. Four different study designs observed that daily application of the melatonin solution to the scalp reduced hair loss and, in some cases, caused new hair growth.
Topical application of the solution containing melatonin, ginkgo biloba and biotin was found to reduce hair loss, and in some cases grow new hair. Incidence of seborrhea was also reduced by the treatment. While the exact mechanism for this result is unknown, if effective, it is likely related to the antioxidative effect of melatonin and/or a melatonin receptor-mediated anti androgenic.